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Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines
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Terpinen-4-ol a naturally occurring monoterpene is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties
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Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[1][2][3] Ethyl acetoacetate is an inhibitor of bacterial biofilm[4]
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Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[1][2][3] Ethyl acetoacetate is an inhibitor of bacterial biofilm[4]
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Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
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Guanabenz Acetate (CAS 23256-50-0) is a small molecule that acts as a selective agonist of the 2-adrenergic receptor subtypes It exhibits notable affinity for the 2a-adrenergic receptor (pEC50 8 25) with moderate activity at the 2b-adrenergic receptor (pEC50 7 01) and lower potency at the 2c-adrenergic receptor (pEC50 5) Through activation of these receptors Guanabenz Acetate modulates adrenergic neurotransmission making it a valuable tool for investigating the physiological and pharmacological functions of 2-adrenergic signaling in biomedical research
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C12 NBD ceramide (d18:1/12:0) is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity.{14063} It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases from a variety of mammalian cell lines also hydrolyze C12 NBD ceramide (d18:1/12:0). Acid ceramidase does not appear to utilize C12 NBD ceramide (d18:1/12:0) as a substrate. The possibility exists forC12 NBD ceramide (d18:1/12:0) to also be applied to the measurement of ceramide kinase and/or sphingomyelin synthase activity.
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Medchemexpress, HY-112847A 5mg Sulfosuccinimidyl oleate sodium CAS: Sulfosuccinimidyl oleate sodium is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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L-NMMA acetate (CAS 53308-83-1) is a broad-spectrum inhibitor of nitric oxide synthases (NOS) exerting inhibitory effects on neuronal (nNOS) endothelial (eNOS) and inducible (iNOS) isoforms It demonstrates submicromolar to low micromolar inhibitory activity against rat nNOS human eNOS and mouse iNOS By selectively blocking NOS-mediated nitric oxide production L-NMMA acetate is widely utilized for dissecting nitric oxide-dependent signaling pathways with research applications spanning studies of tissue injury inflammatory responses and cardiovascular system functions
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